CHC was selected to participate in this landmark research effort (now known as the All of Us Research Program) to collect data from 1 million or more U.S. participants to improve the ability to prevent and treat disease. CHC was part of a pilot program to determine the infrastructure needed to enable a wide variety of health centers to participate in the program. The pilot was critical for bringing underserved individuals, families and communities into the cohort, especially those historically underrepresented in biomedical research.